Stability for Life Science Applications

Emerson Process Management, Rosemount Analytical Division”sPUR-Sense 3800 autoclavable and steam-sterilizable pH sensor isdesigned for stability in life science applications. In simulatedcell-culture process, the PUR-Sense 3800 exhibited sensor drift below0.1 pH after an autoclave of 125 C for 45 minutes. Additional testingshowed continued sensor life after more than 30 autoclave cycles or 50steam cycles. Emerson has worked closely with customers to assuremaximum effectiveness of the PUR-Sense in challenging pharmaceuticalapplications. The reliability and stability of PUR-Sense 3800 in highheat is based upon the unique Emerson PERpH-X(R) and AccuGlass(R)technologies. High temperature can cause deterioration of a pH glasssensing membrane. The AccuGlass pH bulb addresses this issue andresists cracking and aging while exhibiting near theoretical responseeven at extreme pH values. The PUR-Sense reference electrode uses asilver-silver chloride-based reference electrode in combination with anew gelled potassium chloride electrolyte to provide a stable referencepotential through the single proprietary ceramic reference junction.